We use cookies to personalise the offers and shops we show you, remember your favourites, and keep making your experience better every visit. Choose "Accept All" for the full, personalised Virtual Mall, or set your own preferences. You stay in control. See our Privacy Policy.
DefenAge offers award-winning, science-backed anti-aging skincare products featuring revolutionary Defensin molecules to rejuvenate skin and unlock a youthful vitality.
No live deals right now from DefenAge — you can still shop the latest below.
Shop at DefenAgeNew voucher codes, offers and price drops — straight to your inbox. No spam, unsubscribe anytime.
DefenAge is an American skincare innovator, established in 2014 by a dedicated team of regenerative medicine experts. Born from groundbreaking discoveries in cellular biology, the brand quickly became synonymous with advanced anti-aging solutions. Their mission is to share the power of their patented Defensin molecules, aiming to become the number one global anti-aging skincare company for all skin types. DefenAge is committed to honesty, transparency, and excellence, ensuring their customers' needs are always a priority.
At the heart of the DefenAge collection are products designed for comprehensive skin rejuvenation. Their award-winning formulas target key signs of ageing, including fine lines, wrinkles, dark spots, enlarged pores, and loss of firmness. Whether you're seeking to improve skin tone, enhance radiance, or address specific concerns like dullness and dryness, DefenAge offers scientifically-backed solutions. Explore their range to find effective treatments that promote a visibly healthier and more youthful complexion.
DefenAge stands out due to its revolutionary use of Age-Repair Defensins®. These unique molecules work by activating the body's own dormant cells, promoting the natural regeneration of newer, healthier skin. Backed by 15 clinical studies and praised by dermatologists, DefenAge products deliver significant improvements in as little as six weeks, without causing irritation or inflammation. The brand is also a pioneer in clean beauty, meticulously reviewing ingredients and excluding animal- and human-derived substances, ensuring purity and safety.
For customers in the UK, DefenAge products are readily available online, offering a convenient way to access their advanced skincare. The brand prides itself on excellent customer service, available Monday to Friday (Pacific Standard Time). Enhance your shopping experience by joining the Skin Club Rewards Program, where you can earn points and redeem them for exclusive discounts and gift cards, making your journey to radiant skin even more rewarding.
DefenAge was founded in 2014 and is headquartered in USA. It is part of Progenitor Biologics, LLC..
Gift Cards Available
Loyalty Programme
Skin Club Rewards Program
Earn points on purchases, reviews, and referrals, redeemable for discounts or gift cards. New members get 125 bonus points, and every £1 spent earns 1 point, with 750 points equating to a £35 gift card.
International shipping available including UK delivery.
Returns Policy
30-day return policy on unopened products.
Founded
2014
Headquarters
USA
Parent Company
Progenitor Biologics, LLC.
Clean beauty brand free of animal and human-derived ingredients. All products are dermatologist-tested and cruelty-free.
Age-Repair Defensins are bio-synthesised copies of natural human molecules that signal the body to create new skin cells by activating dormant cells and triggering regenerative responses.
Yes, DefenAge completed multicenter double-blind clinical trials showing significant improvement in fine and coarse wrinkles, melanin, and pores with no irritation.
Yes, DefenAge is cruelty-free and all products are dermatologist-tested and free from animal and human-derived ingredients.
No reviews yet for DefenAge
Be the first to write a reviewEarn points on purchases, reviews, and referrals, redeemable for discounts or gift cards. New members get 125 bonus points, and every £1 spent earns 1 point, with 750 points equating to a £35 gift card.
Buy discounted DefenAge gift cards from cashback sites to save even more.
Brought to you by The Virtual Mall, the UK's original online shopping destination, first launched in 1999.
| Standard Delivery | International shipping available including UK delivery. |
| Free Delivery | Not available |
| Click & Collect | Not available |
| Returns Policy | 30-day return policy on unopened products. |
| Student Discount | Not available |
| NHS Discount | Not available |
| Military Discount | Not available |
| International Shipping | Available |
| Payment Methods | Visa, Mastercard, American Express, PayPal |
| Founded | 2014 |
| Headquarters | USA |
Last updated: June 2026
Opens in a new tab
Be the first to review
Dr Jackson's Skincare
Dr Jackson's Skincare offers plant-powered, clean beauty solutions, ethically sourced and dermatologically validated for all skin types.
Sync Beauty
Sync Beauty offers premium, natural lip care and beauty products, formulated in small batches with high-quality ingredients to nourish, protect, and enhance your lips across the UK.
Calecim Professional
Calecim Professional offers advanced skincare and haircare solutions, powered by ethically sourced stem cell technology to rejuvenate your skin and hair.
Forever Feeling
Forever Feeling is a leading British luxury retailer offering iconic health, beauty, and lifestyle products, from skin lightening to sexual wellness, with free worldwide shipping.
HoMEso Europe
HoMEso Europe brings professional-grade skincare, including innovative microneedling kits and rejuvenating creams, directly to your home for accessible, science-backed beauty routines.
Customer Service
1-888-368-5372Customer Service Email
CustomerService@DefenAge.comCustomer Service Hours
Monday to Friday, 9am to 5pm EST